Version 5.4
Bos taurus Gene: HSPA1L
Summary
InnateDB Gene IDBG-633836.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HSPA1L
Gene Name Heat shock 70 kDa protein 1-like
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000025442
Encoded Proteins
IDBP-685569
Heat shock 70 kDa protein 1-like
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000204390:
This gene encodes a 70kDa heat shock protein. In conjunction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which also encode isoforms of the 70kDa heat shock protein. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 23:27334344-27338328
Strand Forward strand
Band
Transcripts
ENSBTAT00000035766 ENSBTAP00000035635
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 93 interaction(s) predicted by orthology.
Predicted by orthology
Total 93 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0005524 ATP binding
GO:0051082 unfolded protein binding
Biological Process
GO:0000902 cell morphogenesis
GO:0006950 response to stress
GO:0007339 binding of sperm to zona pellucida
GO:0042026 protein refolding
Cellular Component
GO:0002199 zona pellucida receptor complex
GO:0005829 cytosol
GO:0008180 COP9 signalosome
GO:0044297 cell body
GO:0072562 blood microparticle
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000204390
View Gene Order
ENSMUSG00000007033
View Gene Order
Pathways
NETPATH
REACTOME
REACT_205580
HSF1-dependent transactivation pathway
REACT_206069
Cellular responses to stress pathway
REACT_225257
Cellular response to heat stress pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_120956
Cellular responses to stress pathway
REACT_200780
Regulation of HSF1-mediated heat shock response pathway
REACT_200624
Attenuation phase pathway
REACT_200775
HSF1-dependent transactivation pathway
REACT_200819
Cellular response to heat stress pathway
REACT_188957
Cellular responses to stress pathway
REACT_213550
HSF1-dependent transactivation pathway
REACT_224790
Cellular response to heat stress pathway
KEGG
hsa04010
MAPK signaling pathway pathway
hsa04612
Antigen processing and presentation pathway
hsa04144
Endocytosis pathway
hsa03040
Spliceosome pathway
hsa04141
Protein processing in endoplasmic reticulum pathway
hsa05145
Toxoplasmosis pathway
mmu04612
Antigen processing and presentation pathway
mmu04010
MAPK signaling pathway pathway
mmu04144
Endocytosis pathway
mmu03040
Spliceosome pathway
mmu04141
Protein processing in endoplasmic reticulum pathway
mmu05145
Toxoplasmosis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.55003
RefSeq NM_001167895 XM_005223678
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca