Version 5.4
| Bos taurus Gene: BEST3 | |||||
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| Summary | |||||
| InnateDB Gene | IDBG-633889.3 | ||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||
| Gene Symbol | BEST3 | ||||
| Gene Name | Uncharacterized protein | ||||
| Synonyms | |||||
| Species | Bos taurus | ||||
| Ensembl Gene | ENSBTAG00000002931 | ||||
| Encoded Proteins |
bestrophin 3
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| Protein Structure | |||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||
| Entrez Gene | |||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000127325:
BEST3 belongs to the bestrophin family of anion channels, which includes BEST1 (MIM 607854), the gene mutant in vitelliform macular dystrophy (VMD; MIM 153700), and 2 other BEST1-like genes, BEST2 (MIM 607335) and BEST4 (MIM 607336). Bestrophins are transmembrane (TM) proteins that share a homology region containing a high content of aromatic residues, including an invariant arg-phe-pro (RFP) motif. The bestrophin genes share a conserved gene structure, with almost identical sizes of the 8 RFP-TM domain-encoding exons and highly conserved exon-intron boundaries. Each of the 4 bestrophin genes has a unique 3-prime end of variable length (Stohr et al., 2002 [PubMed 12032738]; Tsunenari et al., 2003 [PubMed 12907679]).[supplied by OMIM, Mar 2008] |
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| Gene Information | |||||
| Type | Protein coding | ||||
| Genomic Location | Chromosome 5:43995905-44048333 | ||||
| Strand | Forward strand | ||||
| Band | |||||
| Transcripts |
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| Interactions | |||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||
| NETPATH | |||||
| REACTOME |
Stimuli-sensing channels pathway
Transmembrane transport of small molecules pathway
Orphan transporters pathway
Ion channel transport pathway
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| KEGG | |||||
| INOH | |||||
| PID NCI | |||||
| Cross-References | |||||
| SwissProt | |||||
| TrEMBL | E1BF90 | ||||
| UniProt Splice Variant | |||||
| Entrez Gene | 531070 | ||||
| UniGene | |||||
| RefSeq | |||||
| HUGO | HGNC:17105 | ||||
| OMIM | |||||
| CCDS | |||||
| HPRD | |||||
| IMGT | |||||
| EMBL | DAAA02013226 DAAA02013227 | ||||
| GenPept | |||||
| RNA Seq Atlas | 531070 | ||||