InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: SEC61B

Summary

InnateDB Gene

IDBG-634160.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SEC61B

Gene Name

protein transport protein Sec61 subunit beta

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000002457

Encoded Proteins

IDBP-685922

protein transport protein Sec61 subunit beta

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000106803:
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 8:64722966-64731269

Strand

Forward strand

Band

Transcripts

ENSBTAT00000003190

ENSBTAP00000003190

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	25 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0044822	poly(A) RNA binding
GO:0048408	epidermal growth factor binding

Biological Process

GO:0000060	protein import into nucleus, translocation
GO:0030433	ER-associated ubiquitin-dependent protein catabolic process
GO:0030970	retrograde protein transport, ER to cytosol