Version 5.4
Bos taurus Gene: MED11
Summary
InnateDB Gene IDBG-634356.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MED11
Gene Name mediator of RNA polymerase II transcription subunit 11
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000018314
Encoded Proteins
IDBP-686130
mediator of RNA polymerase II transcription subunit 11
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000161920:
MED11 is a component of the Mediator complex, which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II (Sato et al., 2003 [PubMed 12584197]).[supplied by OMIM, Oct 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:27253471-27255303
Strand Reverse strand
Band
Transcripts
ENSBTAT00000024370 ENSBTAP00000024370
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 30 interaction(s) predicted by orthology.
Predicted by orthology
Total 30 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001104 RNA polymerase II transcription cofactor activity
GO:0005515 protein binding
Biological Process
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006366 transcription from RNA polymerase II promoter
Cellular Component
GO:0016592 mediator complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000161920
View Gene Order
ENSMUSG00000018923
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_116145
PPARA activates gene expression pathway
REACT_19241
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) pathway
REACT_22279
Fatty acid, triacylglycerol, and ketone body metabolism pathway
REACT_27161
Transcriptional regulation of white adipocyte differentiation pathway
REACT_111045
Developmental Biology pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_111217
Metabolism pathway
REACT_27166
Transcriptional Regulation of Adipocyte Differentiation in 3T3-L1 Pre-adipocytes pathway
REACT_252217
Transcriptional regulation of white adipocyte differentiation pathway
REACT_200794
Mus musculus biological processes pathway
REACT_256522
Fatty acid, triacylglycerol, and ketone body metabolism pathway
REACT_188937
Metabolism pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
REACT_257219
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) pathway
REACT_198602
PPARA activates gene expression pathway
REACT_188576
Developmental Biology pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1MG57
UniProt Splice Variant
Entrez Gene 511672
UniGene
RefSeq NM_001038084
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02048758
GenPept
RNA Seq Atlas 511672

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca