Version 5.4
Bos taurus Gene: EVL
Summary
InnateDB Gene IDBG-634570.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EVL
Gene Name ena/VASP-like protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000009293
Encoded Proteins
IDBP-686372
Enah/Vasp-like
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000196405:
Gene Information
Type Protein coding
Genomic Location Chromosome 21:66675974-66738876
Strand Forward strand
Band
Transcripts
ENSBTAT00000012242 ENSBTAP00000012242
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.
Predicted by orthology
Total 22 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
GO:0005522 profilin binding
GO:0017124 SH3 domain binding
Biological Process
GO:0008154 actin polymerization or depolymerization
GO:0010633 negative regulation of epithelial cell migration
GO:0030838 positive regulation of actin filament polymerization
GO:0051289 protein homotetramerization
GO:0051496 positive regulation of stress fiber assembly
GO:1900028 negative regulation of ruffle assembly
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005925 focal adhesion
GO:0016020 membrane
GO:0030027 lamellipodium
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000196405
View Gene Order
ENSMUSG00000021262
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_11
TCR pathway
REACTOME
REACT_12623
Generation of second messenger molecules pathway
REACT_19351
Signaling by Robo receptor pathway
REACT_111045
Developmental Biology pathway
REACT_12526
TCR signaling pathway
REACT_18266
Axon guidance pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
REACT_230745
Immune System pathway
REACT_221567
Signaling by Robo receptor pathway
REACT_261444
Axon guidance pathway
REACT_229531
Adaptive Immune System pathway
REACT_188576
Developmental Biology pathway
REACT_225768
Generation of second messenger molecules pathway
REACT_222648
TCR signaling pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E1BHY1
UniProt Splice Variant
Entrez Gene 506201
UniGene Bt.3860
RefSeq NM_001192084 XM_005222156 XM_005222157 XM_005222158 XM_005222160
HUGO HGNC:20234
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02053231 DAAA02053232
GenPept
RNA Seq Atlas 506201

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca