Version 5.4
Homo sapiens Gene: CYP2W1
Summary
InnateDB Gene IDBG-6346.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CYP2W1
Gene Name cytochrome P450, family 2, subfamily W, polypeptide 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000073067
Encoded Proteins
IDBP-6348
cytochrome P450, family 2, subfamily W, polypeptide 1
IDBP-6350
cytochrome P450, family 2, subfamily W, polypeptide 1
IDBP-361072
cytochrome P450, family 2, subfamily W, polypeptide 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:983199-989640
Strand Forward strand
Band p22.3
Transcripts
ENST00000308919 ENSP00000310149
ENST00000340150 ENSP00000344178
ENST00000415893 ENSP00000392581
ENST00000462453
ENST00000468456
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004497 monooxygenase activity
GO:0005506 iron ion binding
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037 heme binding
Biological Process
GO:0006805 xenobiotic metabolic process
GO:0044281 small molecule metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005789 endoplasmic reticulum membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000029541
View Gene Order
ENSBTAG00000017701
Not yet available
Pathways
NETPATH
REACTOME
REACT_13425
Miscellaneous substrates pathway
REACT_13543
Xenobiotics pathway
REACT_13567
Cytochrome P450 - arranged by substrate type pathway
REACT_111217
Metabolism pathway
REACT_13433
Biological oxidations pathway
REACT_13705
Phase 1 - Functionalization of compounds pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.272795
RefSeq NM_017781 XM_005249792
HUGO
OMIM
CCDS CCDS5319
HPRD 07901
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca