Bos taurus Gene: BT.42896
Summary
InnateDB Gene IDBG-634673.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.42896
Gene Name pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000013265
Encoded Proteins
pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000140829:
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a member of the DEAD/H box family of splicing factors. This protein resembles yeast Prp16 more closely than other DEAD/H family members. It is an ATPase and essential for the catalytic step II in pre-mRNA splicing process. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:39146106-39161155
Strand Reverse strand
Band
Transcripts
ENSBTAT00000045480 ENSBTAP00000042866
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.
Predicted by orthology
Total 25 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0008026 ATP-dependent helicase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006200 ATP catabolic process
GO:0008152 metabolic process
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
mRNA 3'-end processing pathway
mRNA Splicing - Major Pathway pathway
Transport of Mature mRNA derived from an Intron-Containing Transcript pathway
Processing of Capped Intron-Containing Pre-mRNA pathway
Cleavage of Growing Transcript in the Termination Region pathway
RNA Polymerase II Transcription Termination pathway
RNA Polymerase II Transcription pathway
Transport of Mature Transcript to Cytoplasm pathway
mRNA Splicing pathway
Gene Expression pathway
KEGG
Spliceosome pathway
Spliceosome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1MVJ1
UniProt Splice Variant
Entrez Gene 520046
UniGene
RefSeq
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02046748 DAAA02046749
GenPept
RNA Seq Atlas 520046