Version 5.4
Bos taurus Gene: METTL1
Summary
InnateDB Gene IDBG-634876.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol METTL1
Gene Name tRNA (guanine-N(7)-)-methyltransferase
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000016908
Encoded Proteins
IDBP-686673
tRNA (guanine-N(7)-)-methyltransferase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000037897:
This gene is similar in sequence to the S. cerevisiae YDL201w gene. The gene product contains a conserved S-adenosylmethionine-binding motif and is inactivated by phosphorylation. Alternative splice variants encoding different protein isoforms have been described for this gene. A pseudogene has been identified on chromosome X. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:56019430-56023032
Strand Forward strand
Band
Transcripts
ENSBTAT00000022487 ENSBTAP00000022487
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000049 tRNA binding
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0008168 methyltransferase activity
GO:0008176 tRNA (guanine-N7-)-methyltransferase activity
GO:0016740 transferase activity
Biological Process
GO:0006400 tRNA modification
GO:0008033 tRNA processing
GO:0030488 tRNA methylation
GO:0032259 methylation
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000037897
View Gene Order
ENSMUSG00000006732
View Gene Order
Cross-References
SwissProt Q2YDF1
TrEMBL
UniProt Splice Variant
Entrez Gene 511197
UniGene Bt.5722
RefSeq NM_001046077
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC110252 BT029912
GenPept AAI10253 ABM06158
RNA Seq Atlas 511197

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca