Bos taurus Gene: POLR2H
Summary
InnateDB Gene IDBG-635056.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol POLR2H
Gene Name DNA-directed RNA polymerases I, II, and III subunit RPABC3
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000040199
Encoded Proteins
polymerase (RNA) II (DNA directed) polypeptide H
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000163882:
This gene encodes one of the essential subunits of RNA polymerase II that is shared by the other two eukaryotic DNA-directed RNA polymerases, I and III. [provided by RefSeq, Jul 2008]
The three eukaryotic RNA polymerases are complex multisubunit enzymes that play a central role in the transcription of nuclear genes. This gene encodes an essential and highly conserved subunit of RNA polymerase II that is shared by the other two eukaryotic DNA-directed RNA polymerases, I and III. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:83437865-83442294
Strand Reverse strand
Band
Transcripts
ENSBTAT00000000606 ENSBTAP00000000606
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 41 interaction(s) predicted by orthology.
Predicted by orthology
Total 41 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001054 RNA polymerase I activity
GO:0001055 RNA polymerase II activity
GO:0001056 RNA polymerase III activity
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006360 transcription from RNA polymerase I promoter
GO:0006366 transcription from RNA polymerase II promoter
GO:0006383 transcription from RNA polymerase III promoter
Cellular Component
GO:0005634 nucleus
GO:0005665 DNA-directed RNA polymerase II, core complex
GO:0005666 DNA-directed RNA polymerase III complex
GO:0005736 DNA-directed RNA polymerase I complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
TNFalpha pathway
REACTOME
Tat-mediated HIV elongation arrest and recovery pathway
Pausing and recovery of Tat-mediated HIV elongation pathway
Viral Messenger RNA Synthesis pathway
RNA Polymerase III Abortive And Retractive Initiation pathway
RNA Polymerase III Transcription Termination pathway
RNA Polymerase III Chain Elongation pathway
RNA Polymerase III Transcription Initiation From Type 3 Promoter pathway
RNA Polymerase III Transcription Initiation From Type 2 Promoter pathway
RNA Polymerase III Transcription Initiation From Type 1 Promoter pathway
RNA Polymerase I Transcription Termination pathway
RNA Polymerase I Chain Elongation pathway
RNA Polymerase I Promoter Escape pathway
RNA Polymerase I Transcription Initiation pathway
mRNA Splicing - Major Pathway pathway
mRNA Splicing - Minor Pathway pathway
Processing of Capped Intron-Containing Pre-mRNA pathway
mRNA Capping pathway
MicroRNA (miRNA) biogenesis pathway
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening pathway
RNA Polymerase II Pre-transcription Events pathway
Formation of RNA Pol II elongation complex pathway
Formation of the Early Elongation Complex pathway
RNA Polymerase II Transcription Elongation pathway
RNA Polymerase II Promoter Escape pathway
RNA Polymerase II Transcription Initiation pathway
RNA Polymerase II Transcription Initiation And Promoter Clearance pathway
RNA Pol II CTD phosphorylation and interaction with CE pathway
Formation of HIV elongation complex in the absence of HIV Tat pathway
HIV Transcription Initiation pathway
Pausing and recovery of HIV elongation pathway
RNA Polymerase II HIV Promoter Escape pathway
Formation of the HIV-1 Early Elongation Complex pathway
Formation of HIV-1 elongation complex containing HIV-1 Tat pathway
Tat-mediated elongation of the HIV-1 transcript pathway
Abortive elongation of HIV-1 transcript in the absence of Tat pathway
RNA Pol II CTD phosphorylation and interaction with CE pathway
HIV elongation arrest and recovery pathway
Transcription of the HIV genome pathway
Late Phase of HIV Life Cycle pathway
Formation of transcription-coupled NER (TC-NER) repair complex pathway
Dual incision reaction in TC-NER pathway
Transcription-coupled NER (TC-NER) pathway
Influenza Infection pathway
RNA Polymerase I Transcription pathway
RNA Polymerase III Transcription Initiation pathway
Innate Immune System pathway
Transcriptional regulation by small RNAs pathway
Epigenetic regulation of gene expression pathway
Influenza Viral RNA Transcription and Replication pathway
RNA Polymerase I Promoter Clearance pathway
NoRC negatively regulates rRNA expression pathway
HIV Transcription Elongation pathway
RNA Polymerase II Transcription pathway
Immune System pathway
HIV Life Cycle pathway
RNA Polymerase III Transcription pathway
HIV Infection pathway
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
Influenza Life Cycle pathway
mRNA Splicing pathway
Cytosolic sensors of pathogen-associated DNA pathway
Nucleotide Excision Repair pathway
Gene Expression pathway
Disease pathway
DNA Repair pathway
Negative epigenetic regulation of rRNA expression pathway
Regulatory RNA pathways pathway
RNA Polymerase II Transcription Initiation And Promoter Clearance pathway
Transcription-coupled NER (TC-NER) pathway
Innate Immune System pathway
RNA Polymerase I Transcription pathway
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
Formation of the Early Elongation Complex pathway
mRNA Splicing pathway
Formation of transcription-coupled NER (TC-NER) repair complex pathway
RNA Polymerase III Transcription Initiation pathway
RNA Polymerase II Transcription Initiation pathway
mRNA Splicing - Minor Pathway pathway
RNA Polymerase II Promoter Escape pathway
RNA Polymerase III Transcription Initiation From Type 1 Promoter pathway
RNA Polymerase I Transcription Termination pathway
Immune System pathway
Nucleotide Excision Repair pathway
Formation of RNA Pol II elongation complex pathway
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening pathway
RNA Polymerase III Transcription Initiation From Type 2 Promoter pathway
RNA Polymerase III Abortive And Retractive Initiation pathway
DNA Repair pathway
Transcriptional regulation by small RNAs pathway
RNA Polymerase II Transcription Elongation pathway
RNA Polymerase II Pre-transcription Events pathway
Cytosolic sensors of pathogen-associated DNA pathway
mRNA Capping pathway
Gene Expression pathway
Regulatory RNA pathways pathway
RNA Polymerase III Transcription Termination pathway
mRNA Splicing - Major Pathway pathway
RNA Polymerase I Promoter Escape pathway
Dual incision reaction in TC-NER pathway
RNA Polymerase I Promoter Clearance pathway
RNA Polymerase I Chain Elongation pathway
Processing of Capped Intron-Containing Pre-mRNA pathway
RNA Polymerase II Transcription pathway
RNA Polymerase III Transcription pathway
RNA Pol II CTD phosphorylation and interaction with CE pathway
RNA Polymerase III Transcription Initiation From Type 3 Promoter pathway
RNA Polymerase I Transcription Initiation pathway
RNA Polymerase III Chain Elongation pathway
KEGG
Pyrimidine metabolism pathway
Purine metabolism pathway
RNA polymerase pathway
Huntington's disease pathway
Cytosolic DNA-sensing pathway pathway
Pyrimidine metabolism pathway
RNA polymerase pathway
Purine metabolism pathway
Huntington's disease pathway
Cytosolic DNA-sensing pathway pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL A8QQK8 F2Z4H3
UniProt Splice Variant
Entrez Gene 505599
UniGene Bt.106863
RefSeq NM_001192065
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC118247 DAAA02001883
GenPept AAI18248
RNA Seq Atlas 505599
Transcript Frequencies
Tag Count based mRNA-Abundances across 87 different Tissues (TPM).

Based on Data from Bovine Gene Atlas

Tag Count based mRNA-Abundances across 87 different Tissues (TPM)

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