Version 5.4
Bos taurus Gene: MAT2A
Summary
InnateDB Gene IDBG-635154.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MAT2A
Gene Name S-adenosylmethionine synthase isoform type-2
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000020873
Encoded Proteins
IDBP-686970
S-adenosylmethionine synthase isoform type-2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000168906:
The protein encoded by this gene catalyzes the production of S-adenosylmethionine (AdoMet) from methionine and ATP. AdoMet is the key methyl donor in cellular processes. [provided by RefSeq, Jun 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:49298517-49305175
Strand Reverse strand
Band
Transcripts
ENSBTAT00000027808 ENSBTAP00000027808
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.
Predicted by orthology
Total 19 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0004478 methionine adenosyltransferase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016740 transferase activity
GO:0046872 metal ion binding
Biological Process
GO:0006556 S-adenosylmethionine biosynthetic process
GO:0006730 one-carbon metabolic process
Cellular Component
GO:0048269 methionine adenosyltransferase complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000168906
View Gene Order
ENSMUSG00000053907
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_6946
Methylation pathway
REACT_6959
Phase II conjugation pathway
REACT_111217
Metabolism pathway
REACT_13433
Biological oxidations pathway
REACT_243247
Phase II conjugation pathway
REACT_188937
Metabolism pathway
REACT_241023
Methylation pathway
REACT_232343
Biological oxidations pathway
KEGG
hsa00270
Cysteine and methionine metabolism pathway
mmu00270
Cysteine and methionine metabolism pathway
INOH
INOH website
Methionine Cysteine metabolism pathway
PID NCI
cmyb_pathway
C-MYB transcription factor network
Cross-References
SwissProt
TrEMBL A7E3T7
UniProt Splice Variant
Entrez Gene 527403
UniGene Bt.108992 Bt.64780
RefSeq NM_001101131
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BT030708 DAAA02031137 DAAA02031138
GenPept ABS45024
RNA Seq Atlas 527403

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca