Bos taurus Gene: BT.21593 | |||||||||||||
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Summary | |||||||||||||
InnateDB Gene | IDBG-635506.3 | ||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
Gene Symbol | BT.21593 | ||||||||||||
Gene Name | ATP-binding cassette sub-family B member 7, mitochondrial | ||||||||||||
Synonyms | |||||||||||||
Species | Bos taurus | ||||||||||||
Ensembl Gene | ENSBTAG00000011028 | ||||||||||||
Encoded Proteins |
Uncharacterized protein
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Protein Structure | |||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||
Entrez Gene | |||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000131269:
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been associated with mitochondrial iron accumulation and isodicentric (X)(q13) and sideroblastic anemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2012] |
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Gene Information | |||||||||||||
Type | Protein coding | ||||||||||||
Genomic Location | Chromosome X:81008166-81167688 | ||||||||||||
Strand | Forward strand | ||||||||||||
Band | |||||||||||||
Transcripts |
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Interactions | |||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||||||||
NETPATH | |||||||||||||
REACTOME |
Mitochondrial ABC transporters pathway
ABC-family proteins mediated transport pathway
Cytosolic iron-sulfur cluster assembly pathway
Transmembrane transport of small molecules pathway
Metabolism pathway
Mitochondrial ABC transporters pathway
Metabolism pathway
Transmembrane transport of small molecules pathway
Cytosolic iron-sulfur cluster assembly pathway
ABC-family proteins mediated transport pathway
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KEGG |
ABC transporters pathway
ABC transporters pathway
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INOH | |||||||||||||
PID NCI | |||||||||||||
Cross-References | |||||||||||||
SwissProt | |||||||||||||
TrEMBL | E1BPL3 | ||||||||||||
UniProt Splice Variant | |||||||||||||
Entrez Gene | 533669 | ||||||||||||
UniGene | Bt.21593 | ||||||||||||
RefSeq | NM_001192783 XM_005227962 XM_005227963 | ||||||||||||
HUGO | HGNC:48 | ||||||||||||
OMIM | |||||||||||||
CCDS | |||||||||||||
HPRD | |||||||||||||
IMGT | |||||||||||||
EMBL | DAAA02072525 DAAA02072526 DAAA02072527 DAAA02072528 DAAA02072529 DAAA02072530 | ||||||||||||
GenPept | |||||||||||||
RNA Seq Atlas | 533669 | ||||||||||||