Bos taurus Gene: BRP44L
Summary
InnateDB Gene IDBG-635842.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BRP44L
Gene Name Mitochondrial pyruvate carrier 1
Synonyms MPC1
Species Bos taurus
Ensembl Gene ENSBTAG00000027879
Encoded Proteins
Brain protein 44-like protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000060762:
The protein encoded by this gene is part of an MPC1/MPC2 heterodimer that is responsible for transporting pyruvate into mitochondria. The encoded protein is found in the inner mitochondrial membrane. Defects in this gene are a cause of mitochondrial pyruvate carrier deficiency. Several transcript variants, some protein coding and one non-protein coding, have been found for this gene. [provided by RefSeq, Aug 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:102880277-102893601
Strand Reverse strand
Band
Transcripts
ENSBTAT00000040201 ENSBTAP00000039979
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0050833 pyruvate transmembrane transporter activity
Biological Process
GO:0006090 pyruvate metabolic process
GO:0006810 transport
GO:0006850 mitochondrial pyruvate transport
GO:1901475 pyruvate transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathways
NETPATH
REACTOME
The citric acid (TCA) cycle and respiratory electron transport pathway
Pyruvate metabolism pathway
Metabolism pathway
Pyruvate metabolism and Citric Acid (TCA) cycle pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Pyruvate metabolism pathway
Pyruvate metabolism and Citric Acid (TCA) cycle pathway
The citric acid (TCA) cycle and respiratory electron transport pathway
Metabolism pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001077042 XM_005211111 XM_005211113
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas