Bos taurus Gene: PMEL17 | |||||||||
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Summary | |||||||||
InnateDB Gene | IDBG-636420.3 | ||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
Gene Symbol | PMEL17 | ||||||||
Gene Name | melanocyte protein PMEL precursor | ||||||||
Synonyms | PMEL17; RPE1; SILV | ||||||||
Species | Bos taurus | ||||||||
Ensembl Gene | ENSBTAG00000004019 | ||||||||
Encoded Proteins |
melanocyte protein Pmel 17 precursor
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Protein Structure | |||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||
Entrez Gene | |||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000185664:
This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2011] |
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Gene Information | |||||||||
Type | Protein coding | ||||||||
Genomic Location | Chromosome 5:57669835-57677941 | ||||||||
Strand | Forward strand | ||||||||
Band | |||||||||
Transcripts |
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Interactions | |||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Cross-References | |||||||||
SwissProt | |||||||||
TrEMBL | A3F9J0 A3F9J1 F1MFK3 | ||||||||
UniProt Splice Variant | |||||||||
Entrez Gene | 281487 | ||||||||
UniGene | Bt.5091 | ||||||||
RefSeq | NM_001080215 XM_005206504 XM_005206505 | ||||||||
HUGO | |||||||||
OMIM | |||||||||
CCDS | |||||||||
HPRD | |||||||||
IMGT | |||||||||
EMBL | DAAA02013536 EF363684 EF363685 | ||||||||
GenPept | ABN13416 ABN13417 | ||||||||
RNA Seq Atlas | 281487 | ||||||||