Version 5.4
Bos taurus Gene: RP2
Summary
InnateDB Gene IDBG-636465.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RP2
Gene Name protein XRP2
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000005496
Encoded Proteins
IDBP-688384
protein XRP2
IDBP-688385
protein XRP2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000102218:
The RP2 locus has been implicated as one cause of X-linked retinitis pigmentosa. The predicted gene product shows homology with human cofactor C, a protein involved in the ultimate step of beta-tubulin folding. Progressive retinal degeneration may therefore be due to the accumulation of incorrectly-folded photoreceptor or neuron-specific tubulin isoforms followed by progressive cell death [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome X:90487298-90537534
Strand Forward strand
Band
Transcripts
ENSBTAT00000007225 ENSBTAP00000007225
ENSBTAT00000049336 ENSBTAP00000046240
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0004550 nucleoside diphosphate kinase activity
GO:0005096 GTPase activator activity
GO:0005515 protein binding
GO:0005524 ATP binding
Biological Process
GO:0000902 cell morphogenesis
GO:0006165 nucleoside diphosphate phosphorylation
GO:0006183 GTP biosynthetic process
GO:0006228 UTP biosynthetic process
GO:0006241 CTP biosynthetic process
GO:0006892 post-Golgi vesicle-mediated transport
GO:0007010 cytoskeleton organization
Cellular Component
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005814 centriole
GO:0005886 plasma membrane
GO:0031410 cytoplasmic vesicle
GO:0036064 ciliary basal body
GO:0070062 extracellular vesicular exosome
GO:1990075 periciliary membrane compartment
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000102218
View Gene Order
ENSMUSG00000060090
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.42059
RefSeq NM_001035403 XM_005228079
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca