InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: APIP

Summary

InnateDB Gene

IDBG-636552.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

APIP

Gene Name

Probable methylthioribulose-1-phosphate dehydratase

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000018257

Encoded Proteins

IDBP-688479

Probable methylthioribulose-1-phosphate dehydratase

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000149089:
APIP is an APAF1 (MIM 602233)-interacting protein that acts as a negative regulator of ischemic/hypoxic injury (Cho et al., 2004 [PubMed 15262985]).[supplied by OMIM, Dec 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 15:66207587-66231698

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000024300

ENSBTAP00000024300

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.

Predicted by orthology
Total	11 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0016829	lyase activity
GO:0042802	identical protein binding
GO:0046570	methylthioribulose 1-phosphate dehydratase activity
GO:0046872	metal ion binding

Biological Process

GO:0006915	apoptotic process
GO:0008652	cellular amino acid biosynthetic process
GO:0009086	methionine biosynthetic process
GO:0019284	L-methionine biosynthetic process from S-adenosylmethionine
GO:0019509	L-methionine biosynthetic process from methylthioadenosine
GO:0043066	negative regulation of apoptotic process
GO:0070372	regulation of ERK1 and ERK2 cascade