InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: CDC7L1

Summary

InnateDB Gene

IDBG-636696.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CDC7L1

Gene Name

cell division cycle 7-related protein kinase

Synonyms

CDC7L1

Species

Bos taurus

Ensembl Gene

ENSBTAG00000016307

Encoded Proteins

IDBP-688647

cell division cycle 7-related protein kinase

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000097046:
This gene encodes a cell division cycle protein with kinase activity that is critical for the G1/S transition. The yeast homolog is also essential for initiation of DNA replication as cell division occurs. Overexpression of this gene product may be associated with neoplastic transformation for some tumors. Multiple alternatively spliced transcript variants that encode the same protein have been detected. [provided by RefSeq, Aug 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 3:52014639-52039702

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000021696

ENSBTAP00000021696

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 26 interaction(s) predicted by orthology.

Predicted by orthology
Total	26 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016301	kinase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups

Biological Process

GO:0006468	protein phosphorylation
GO:0008284	positive regulation of cell proliferation
GO:0010571	positive regulation of nuclear cell cycle DNA replication
GO:0010971	positive regulation of G2/M transition of mitotic cell cycle
GO:0044770	cell cycle phase transition
GO:0051301	cell division