Version 5.4
| Bos taurus Gene: ELK1 | |||||||||||||||||
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| Summary | |||||||||||||||||
| InnateDB Gene | IDBG-636750.3 | ||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||
| Gene Symbol | ELK1 | ||||||||||||||||
| Gene Name | ETS domain-containing protein Elk-1 | ||||||||||||||||
| Synonyms | |||||||||||||||||
| Species | Bos taurus | ||||||||||||||||
| Ensembl Gene | ENSBTAG00000015817 | ||||||||||||||||
| Encoded Proteins |
ELK1, member of ETS oncogene family
ELK1, member of ETS oncogene family
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| Protein Structure | |||||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||
| Entrez Gene | |||||||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000126767:
This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum response element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. This gene produces multiple isoforms by using alternative translational start codons and by alternative splicing. Related pseudogenes have been identified on chromosomes 7 and 14. [provided by RefSeq, Mar 2012] |
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| Gene Information | |||||||||||||||||
| Type | Protein coding | ||||||||||||||||
| Genomic Location | Chromosome X:91452108-91466887 | ||||||||||||||||
| Strand | Reverse strand | ||||||||||||||||
| Band | |||||||||||||||||
| Transcripts |
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| Interactions | |||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 27 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||||||||||||
| NETPATH |
EGFR1 pathway
ID pathway
KitReceptor pathway
BCR pathway
IL2 pathway
IL4 pathway
IL5 pathway
Leptin pathway
Prolactin pathway
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| REACTOME |
ERK/MAPK targets pathway
MyD88-independent cascade pathway
Toll Like Receptor 3 (TLR3) Cascade pathway
MyD88:Mal cascade initiated on plasma membrane pathway
Toll Like Receptor TLR1:TLR2 Cascade pathway
Toll Like Receptor TLR6:TLR2 Cascade pathway
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation pathway
MyD88 dependent cascade initiated on endosome pathway
Toll Like Receptor 9 (TLR9) Cascade pathway
MyD88 cascade initiated on plasma membrane pathway
Toll Like Receptor 10 (TLR10) Cascade pathway
Toll Like Receptor 4 (TLR4) Cascade pathway
Toll Like Receptor 5 (TLR5) Cascade pathway
Signalling by NGF pathway
Toll Like Receptor 7/8 (TLR7/8) Cascade pathway
Innate Immune System pathway
Toll Like Receptor 2 (TLR2) Cascade pathway
Toll-Like Receptors Cascades pathway
Signal Transduction pathway
MAP kinase activation in TLR cascade pathway
Immune System pathway
NGF signalling via TRKA from the plasma membrane pathway
Activated TLR4 signalling pathway
Nuclear Events (kinase and transcription factor activation) pathway
MAPK targets/ Nuclear events mediated by MAP kinases pathway
TRIF-mediated TLR3/TLR4 signaling pathway
Toll Like Receptor 3 (TLR3) Cascade pathway
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation pathway
Toll Like Receptor 2 (TLR2) Cascade pathway
Innate Immune System pathway
MAPK targets/ Nuclear events mediated by MAP kinases pathway
MyD88 cascade initiated on plasma membrane pathway
ERK/MAPK targets pathway
Toll Like Receptor TLR1:TLR2 Cascade pathway
MAP kinase activation in TLR cascade pathway
Immune System pathway
Toll Like Receptor 5 (TLR5) Cascade pathway
Toll Like Receptor TLR6:TLR2 Cascade pathway
Toll Like Receptor 9 (TLR9) Cascade pathway
Toll-Like Receptors Cascades pathway
MyD88 dependent cascade initiated on endosome pathway
Signalling by NGF pathway
Activated TLR4 signalling pathway
NGF signalling via TRKA from the plasma membrane pathway
MyD88-independent cascade pathway
Signal Transduction pathway
Toll Like Receptor 7/8 (TLR7/8) Cascade pathway
MyD88:Mal cascade initiated on plasma membrane pathway
TRIF-mediated TLR3/TLR4 signaling pathway
Nuclear Events (kinase and transcription factor activation) pathway
Toll Like Receptor 10 (TLR10) Cascade pathway
Toll Like Receptor 4 (TLR4) Cascade pathway
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| KEGG |
GnRH signaling pathway pathway
ErbB signaling pathway pathway
MAPK signaling pathway pathway
Endometrial cancer pathway
Insulin signaling pathway pathway
Focal adhesion pathway
Prion diseases pathway
Leishmaniasis pathway
Endometrial cancer pathway
ErbB signaling pathway pathway
Insulin signaling pathway pathway
GnRH signaling pathway pathway
MAPK signaling pathway pathway
Focal adhesion pathway
Prion diseases pathway
Leishmaniasis pathway
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| INOH |
FGF signaling pathway pathway
Insulin receptor signaling pathway
VEGF signaling pathway pathway
HGF signaling pathway pathway
EGF signaling pathway pathway
NGF signaling pathway pathway
IGF1 signaling pathway pathway
PDGF signaling pathway pathway
FGF8 signaling (Mouse) pathway
FGF signaling pathway pathway
Insulin receptor signaling pathway
VEGF signaling pathway pathway
HGF signaling pathway pathway
EGF signaling pathway pathway
NGF signaling pathway pathway
PDGF signaling pathway pathway
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| PID NCI |
Trk receptor signaling mediated by the MAPK pathway
Downstream signaling in naïve CD8+ T cells
S1P2 pathway
ErbB1 downstream signaling
HIF-2-alpha transcription factor network
BCR signaling pathway
Angiopoietin receptor Tie2-mediated signaling
Ras signaling in the CD4+ TCR pathway
PDGFR-alpha signaling pathway
PDGFR-beta signaling pathway
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| Cross-References | |||||||||||||||||
| SwissProt | |||||||||||||||||
| TrEMBL | |||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||
| Entrez Gene | |||||||||||||||||
| UniGene | Bt.64911 | ||||||||||||||||
| RefSeq | NM_001191236 | ||||||||||||||||
| HUGO | |||||||||||||||||
| OMIM | |||||||||||||||||
| CCDS | |||||||||||||||||
| HPRD | |||||||||||||||||
| IMGT | |||||||||||||||||
| EMBL | |||||||||||||||||
| GenPept | |||||||||||||||||
| RNA Seq Atlas | |||||||||||||||||