Version 5.4
Homo sapiens Gene: NMD3
Summary
InnateDB Gene IDBG-63694.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NMD3
Gene Name NMD3 homolog (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000169251
Encoded Proteins
IDBP-63696
NMD3 homolog (S. cerevisiae)
IDBP-481093
NMD3 homolog (S. cerevisiae)
IDBP-480505
NMD3 homolog (S. cerevisiae)
IDBP-475074
NMD3 homolog (S. cerevisiae)
IDBP-474264
NMD3 homolog (S. cerevisiae)
IDBP-484882
NMD3 homolog (S. cerevisiae)
IDBP-474226
NMD3 homolog (S. cerevisiae)
IDBP-484625
NMD3 homolog (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Ribosomes are composed of 60S and 40S subunits that are assembled in the nucleolus and exported to the cytoplasm through nuclear pore complexes in the nuclear envelope. NMD3 is an adaptor for 60S subunit export via the CRM1 (XPO1; MIM 602559) pathway (Trotta et al., 2003 [PubMed 12773398]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:161104696-161253532
Strand Forward strand
Band q26.1
Transcripts
ENST00000351193 ENSP00000307525
ENST00000468606 ENSP00000418852
ENST00000460503 ENSP00000418980
ENST00000493066 ENSP00000419030
ENST00000473909
ENST00000472947 ENSP00000417559
ENST00000463518 ENSP00000418908
ENST00000476237 ENSP00000419647
ENST00000460469 ENSP00000419004
ENST00000478160
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0030674 protein binding, bridging
GO:0043023 ribosomal large subunit binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000055 ribosomal large subunit export from nucleus
GO:0015031 protein transport
Cellular Component
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000027787
View Gene Order
ENSBTAG00000016228
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa03013
RNA transport pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.592863 Hs.598836 Hs.718722
RefSeq NM_015938 XM_005247511 XM_005247512
HUGO
OMIM
CCDS CCDS3194
HPRD 13026
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca