Version 5.4
Homo sapiens Gene: TBC1D8
Summary
InnateDB Gene IDBG-63709.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TBC1D8
Gene Name TBC1 domain family, member 8 (with GRAM domain)
Synonyms AD3; HBLP1; TBC1D8A; VRP
Species Homo sapiens
Ensembl Gene ENSG00000204634
Encoded Proteins
IDBP-63711
TBC1 domain family, member 8 (with GRAM domain)
IDBP-295143
TBC1 domain family, member 8 (with GRAM domain)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 2:101007617-101252866
Strand Reverse strand
Band q11.2
Transcripts
ENST00000376840 ENSP00000366036
ENST00000409318 ENSP00000386856
ENST00000494011
ENST00000473937
ENST00000485875
ENST00000481317
ENST00000487392
ENST00000463469
ENST00000462819
ENST00000485851
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005097 Rab GTPase activator activity
GO:0005509 calcium ion binding
Biological Process
GO:0008015 blood circulation
GO:0008284 positive regulation of cell proliferation
GO:0032313 regulation of Rab GTPase activity
GO:0032851 positive regulation of Rab GTPase activity
Cellular Component
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000003134
View Gene Order
ENSBTAG00000025898
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.442657
RefSeq NM_001102426 XM_005263862 XM_005263863 XM_005263864
HUGO
OMIM
CCDS CCDS46375
HPRD 06752
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca