Version 5.4
Bos taurus Gene: SGMS1
Summary
InnateDB Gene IDBG-637178.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SGMS1
Gene Name phosphatidylcholine:ceramide cholinephosphotransferase 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000011748
Encoded Proteins
IDBP-689186
sphingomyelin synthase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000198964:
The protein encoded by this gene is predicted to be a five-pass transmembrane protein. This gene may be predominately expressed in brain. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 26:8735912-8775858
Strand Reverse strand
Band
Transcripts
ENSBTAT00000015599 ENSBTAP00000015599
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0005515 protein binding
GO:0033188 sphingomyelin synthase activity
GO:0047493 ceramide cholinephosphotransferase activity
Biological Process
GO:0006686 sphingomyelin biosynthetic process
GO:0016049 cell growth
GO:2001237 negative regulation of extrinsic apoptotic signaling pathway
Cellular Component
GO:0000138 Golgi trans cisterna
GO:0016020 membrane
GO:0030173 integral component of Golgi membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000198964
View Gene Order
ENSMUSG00000040451
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_115810
Sphingolipid de novo biosynthesis pathway
REACT_19323
Sphingolipid metabolism pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_111217
Metabolism pathway
REACT_198151
Sphingolipid de novo biosynthesis pathway
REACT_188937
Metabolism pathway
REACT_245163
Sphingolipid metabolism pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
KEGG
hsa00600
Sphingolipid metabolism pathway
mmu00600
Sphingolipid metabolism pathway
INOH
PID NCI
il2_pi3kpathway
IL2 signaling events mediated by PI3K
Cross-References
SwissProt
TrEMBL F1MF31
UniProt Splice Variant
Entrez Gene 533538
UniGene Bt.88680
RefSeq NM_001206135 XM_005225376 XM_005225377 XM_005225378 XM_005225379 XM_005225380 XM_005225381 XM_005225382 XM_005225383 XM_005225384 XM_005225385 XM_005225386 XM_005225387 XM_005225388 XM_005225389 XM_005225390 XM_005225391 XM_005225392 XM_005225393 XM_005225394 XM_005225395 XM_005225396 XM_005225397 XM_005225398 XM_005225399 XM_005225400 XM_005225401 XM_005225402 XM_005225403
HUGO HGNC:29799
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02058701
GenPept
RNA Seq Atlas 533538

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca