Version 5.4
Bos taurus Gene: ABCC6
Summary
InnateDB Gene IDBG-637327.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ABCC6
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000015191
Encoded Proteins
IDBP-689517
ATP-binding cassette, sub-family C (CFTR/MRP), member 6
IDBP-689519
ATP-binding cassette, sub-family C (CFTR/MRP), member 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000091262:
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein, a member of the MRP subfamily, is involved in multi-drug resistance. Mutations in this gene cause pseudoxanthoma elasticum. Alternatively spliced transcript variants that encode different proteins have been described for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 25:14577546-14643306
Strand Reverse strand
Band
Transcripts
ENSBTAT00000050284 ENSBTAP00000047017
ENSBTAT00000063479 ENSBTAP00000055881
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0005215 transporter activity
GO:0005524 ATP binding
GO:0016887 ATPase activity
GO:0017111 nucleoside-triphosphatase activity
GO:0042626 ATPase activity, coupled to transmembrane movement of substances
Biological Process
GO:0006200 ATP catabolic process
GO:0006810 transport
GO:0008152 metabolic process
GO:0055085 transmembrane transport
Cellular Component
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000091262
View Gene Order
ENSMUSG00000030834
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_15480
ABC-family proteins mediated transport pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_253400
Transmembrane transport of small molecules pathway
REACT_237882
ABC-family proteins mediated transport pathway
KEGG
hsa02010
ABC transporters pathway
mmu02010
ABC transporters pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL G3N1X7
UniProt Splice Variant
Entrez Gene 100337270
UniGene Bt.102320 Bt.64684
RefSeq NM_001276370 XM_005224681 XM_005224683
HUGO HGNC:57
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02057563 DAAA02057564 DAAA02057565
GenPept
RNA Seq Atlas 100337270

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca