Version 5.4
Bos taurus Gene: ACTA2
Summary
InnateDB Gene IDBG-637330.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ACTA2
Gene Name Actin, aortic smooth muscle
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000014614
Encoded Proteins
IDBP-689349
Actin, aortic smooth muscle
IDBP-689351
Actin, aortic smooth muscle
IDBP-689354
Actin, aortic smooth muscle
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 26:10662362-10714982
Strand Reverse strand
Band
Transcripts
ENSBTAT00000037115 ENSBTAP00000036954
ENSBTAT00000029208 ENSBTAP00000046205
ENSBTAT00000019461 ENSBTAP00000019461
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0005515 protein binding
GO:0005524 ATP binding
Biological Process
GO:0008217 regulation of blood pressure
GO:0009615 response to virus
GO:0014829 vascular smooth muscle contraction
GO:0030240 skeletal muscle thin filament assembly
GO:0048741 skeletal muscle fiber development
GO:0072144 glomerular mesangial cell development
Cellular Component
GO:0001725 stress fiber
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005865 striated muscle thin filament
GO:0005884 actin filament
GO:0015629 actin cytoskeleton
GO:0030485 smooth muscle contractile fiber
GO:0043234 protein complex
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_213099
Muscle contraction pathway
REACT_217010
Smooth Muscle Contraction pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL G8JKX4
UniProt Splice Variant
Entrez Gene 515610
UniGene Bt.37349
RefSeq NM_001034502 XM_005225364
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02058730
GenPept
RNA Seq Atlas 281595 515610

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca