Bos taurus Gene: FASTK
Summary
InnateDB Gene IDBG-637673.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FASTK
Gene Name fas-activated serine/threonine kinase
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000011228
Encoded Proteins
Fas-activated serine/threonine kinase isoform 1
Fas-activated serine/threonine kinase isoform 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000164896:
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:114450706-114455203
Strand Reverse strand
Band
Transcripts
ENSBTAT00000043835 ENSBTAP00000041377
ENSBTAT00000014911 ENSBTAP00000014911
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005515 protein binding
Biological Process
GO:0006468 protein phosphorylation
GO:0043484 regulation of RNA splicing
Cellular Component
GO:0005739 mitochondrion
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Cross-References
SwissProt
TrEMBL F1MQ72 F1N4L0
UniProt Splice Variant
Entrez Gene 509781
UniGene
RefSeq NM_001035077 XM_005205814 XM_005205815 XM_005205816
HUGO HGNC:24676
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02012014
GenPept
RNA Seq Atlas 509781