Homo sapiens Gene: IL4I1
Summary
InnateDB Gene IDBG-63774.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IL4I1
Gene Name interleukin 4 induced 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000104951
Encoded Proteins
interleukin 4 induced 1
interleukin 4 induced 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein with limited similarity to L-amino acid oxidase which contains the conserved amino acids thought to be involved in catalysis and binding of flavin adenine dinucleotide (FAD) cofactor. The expression of this gene can be induced by interleukin 4 in B cells, however, expression of transcripts containing the first two exons of the upstream gene is found in other cell types. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:49889654-49929539
Strand Reverse strand
Band q13.33
Transcripts
ENST00000341114 ENSP00000342557
ENST00000391826 ENSP00000375702
ENST00000596011 ENSP00000472786
ENST00000601717 ENSP00000469467
ENST00000595948 ENSP00000472474
ENST00000593956 ENSP00000470120
ENST00000597295 ENSP00000469841
ENST00000596022 ENSP00000471950
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0001716 L-amino-acid oxidase activity
GO:0016491 oxidoreductase activity
GO:0050660 flavin adenine dinucleotide binding
Biological Process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005576 extracellular region
GO:0005764 lysosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Abnormal metabolism in phenylketonuria pathway
Disease pathway
KEGG
Phenylalanine metabolism pathway
Valine, leucine and isoleucine degradation pathway
Phenylalanine, tyrosine and tryptophan biosynthesis pathway
Tryptophan metabolism pathway
Tyrosine metabolism pathway
Cysteine and methionine metabolism pathway
Alanine, aspartate and glutamate metabolism pathway
INOH
PID NCI
Cross-References
SwissProt Q96RQ9
TrEMBL M0R1L1
UniProt Splice Variant
Entrez Gene 259307
UniGene Hs.741750
RefSeq NM_001258017 NM_172374 NM_001258018 NM_152899
HUGO HGNC:19094
OMIM 609742
CCDS CCDS12786 CCDS12787
HPRD 17146
IMGT
EMBL AC011452 AC118342 AF293462 AF293463 AJ880386 AJ880387 AJ880388 AK074097 AY358933 BC064378 BC090852 CH471177 DQ079587 DQ079588 DQ079589
GenPept AAH64378 AAH90852 AAK73362 AAK73363 AAQ89292 AAZ32711 AAZ32712 AAZ32713 BAB84923 CAI54291 CAI54292 CAI54293 EAW52575
RNA Seq Atlas 259307