Version 5.4
| Bos taurus Gene: BT.22969 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-637881.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | BT.22969 | ||||||||
| Gene Name | factor XIIa inhibitor precursor | ||||||||
| Synonyms | C1NH | ||||||||
| Species | Bos taurus | ||||||||
| Ensembl Gene | ENSBTAG00000016267 | ||||||||
| Encoded Proteins |
factor XIIa inhibitor precursor
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| InnateDB Annotation from Orthologs | |||||||||
| Summary |
[Homo sapiens] A likely regulator of MASP2
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| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000149131:
This gene encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 15:82159474-82172143 | ||||||||
| Strand | Forward strand | ||||||||
| Band | |||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
Intrinsic Pathway pathway
Platelet degranulation pathway
Response to elevated platelet cytosolic Ca2+ pathway
Formation of Fibrin Clot (Clotting Cascade) pathway
Platelet activation, signaling and aggregation pathway
Hemostasis pathway
Platelet degranulation pathway
Hemostasis pathway
Platelet activation, signaling and aggregation pathway
Intrinsic Pathway pathway
Formation of Fibrin Clot (Clotting Cascade) pathway
Response to elevated platelet cytosolic Ca2+ pathway
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| KEGG |
Complement and coagulation cascades pathway
Complement and coagulation cascades pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | E1BMJ0 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 281035 | ||||||||
| UniGene | Bt.22969 | ||||||||
| RefSeq | NM_174821 XM_005216527 | ||||||||
| HUGO | HGNC:1228 | ||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | DAAA02041763 | ||||||||
| GenPept | |||||||||
| RNA Seq Atlas | 281035 | ||||||||