Version 5.4
Bos taurus Gene: FLVCR1
Summary
InnateDB Gene IDBG-638056.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FLVCR1
Gene Name feline leukemia virus subgroup C receptor-related protein 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000015974
Encoded Proteins
IDBP-690115
feline leukemia virus subgroup C cellular receptor 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000162769:
This gene encodes a member of the major facilitator superfamily of transporter proteins. The encoded protein is a heme transporter that may play a critical role in erythropoiesis by protecting developing erythroid cells from heme toxicity. This gene may play a role in posterior column ataxia with retinitis pigmentosa and the hematological disorder Diamond-Blackfan syndrome. [provided by RefSeq, Jan 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:72570592-72596973
Strand Reverse strand
Band
Transcripts
ENSBTAT00000021251 ENSBTAP00000021251
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0015232 heme transporter activity
Biological Process
GO:0001568 blood vessel development
GO:0001701 in utero embryonic development
GO:0006839 mitochondrial transport
GO:0015886 heme transport
GO:0030218 erythrocyte differentiation
GO:0035108 limb morphogenesis
GO:0035264 multicellular organism growth
GO:0042733 embryonic digit morphogenesis
GO:0046620 regulation of organ growth
GO:0048536 spleen development
GO:0048704 embryonic skeletal system morphogenesis
GO:0055085 transmembrane transport
GO:0060323 head morphogenesis
GO:0097037 heme export
Cellular Component
GO:0005739 mitochondrion
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000162769
View Gene Order
ENSMUSG00000066595
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_25060
Iron uptake and transport pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_205755
Iron uptake and transport pathway
REACT_253400
Transmembrane transport of small molecules pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E1B7A6
UniProt Splice Variant
Entrez Gene 533317
UniGene Bt.77428
RefSeq NM_001206019
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02043747 DAAA02043748
GenPept
RNA Seq Atlas 533317

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca