Version 5.4
Bos taurus Gene: PAXIP1
Summary
InnateDB Gene IDBG-638164.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PAXIP1
Gene Name PAX-interacting protein 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000017505
Encoded Proteins
IDBP-690252
PAX-interacting protein 1
IDBP-690260
PAX-interacting protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000157212:
This gene is a member of the paired box (PAX) gene family and encodes a nuclear protein with six BRCT (breast cancer carboxy-terminal) domains. This protein plays a critical role in maintaining genome stability, condensation of chromatin and progression through mitosis. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:117819455-117851230
Strand Reverse strand
Band
Transcripts
ENSBTAT00000023287 ENSBTAP00000023287
ENSBTAT00000064484 ENSBTAP00000055051
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 241 interaction(s) predicted by orthology.
Predicted by orthology
Total 241 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0000416 positive regulation of histone H3-K36 methylation
GO:0001570 vasculogenesis
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006974 cellular response to DNA damage stimulus
GO:0010212 response to ionizing radiation
GO:0030330 DNA damage response, signal transduction by p53 class mediator
GO:0031398 positive regulation of protein ubiquitination
GO:0035066 positive regulation of histone acetylation
GO:0043542 endothelial cell migration
GO:0045830 positive regulation of isotype switching
GO:0051568 histone H3-K4 methylation
GO:0051571 positive regulation of histone H3-K4 methylation
GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter
GO:0060612 adipose tissue development
GO:0060717 chorion development
Cellular Component
GO:0005634 nucleus
GO:0016363 nuclear matrix
GO:0035097 histone methyltransferase complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000157212
View Gene Order
ENSMUSG00000002221
View Gene Order
Cross-References
SwissProt A0JNA8
TrEMBL F1N0E0
UniProt Splice Variant
Entrez Gene 513213
UniGene Bt.21228
RefSeq NM_001077917
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC126589 DAAA02012116
GenPept AAI26590
RNA Seq Atlas 513213

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca