Version 5.4
Bos taurus Gene: PTCHD1
Summary
InnateDB Gene IDBG-638443.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PTCHD1
Gene Name patched domain-containing protein 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000020987
Encoded Proteins
IDBP-690512
patched domain containing 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000165186:
This gene encodes a membrane protein with a patched domain. The encoded protein is similar to Drosophila proteins which act as receptors for the morphogen sonic hedgehog. Deletions in this gene, which is located on the X chromosome, are associated with intellectual disability and autism (PMID: 21091464, PMID: 20844286). [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome X:126856700-126939882
Strand Reverse strand
Band
Transcripts
ENSBTAT00000027948 ENSBTAP00000027948
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0008158 hedgehog receptor activity
Biological Process
GO:0007224 smoothened signaling pathway
GO:0050890 cognition
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000165186
View Gene Order
ENSMUSG00000041552
View Gene Order
Cross-References
SwissProt
TrEMBL G5E5Q5
UniProt Splice Variant
Entrez Gene 536443
UniGene Bt.106548
RefSeq NM_001192881
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02074381 DAAA02074382 DAAA02074383 DAAA02074384
GenPept
RNA Seq Atlas 536443

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca