Bos taurus Gene: BT.53032
Summary
InnateDB Gene IDBG-638590.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.53032
Gene Name crossover junction endonuclease EME1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000021723
Encoded Proteins
essential meiotic endonuclease 1 homolog 1
essential meiotic endonuclease 1 homolog 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000154920:
This gene encodes a protein that complexes with methyl methanesulfonate-sensitive UV-sensitive 81 protein to form an endonuclease complex. The encoded protein interacts with specifc DNA structures including nicked Holliday junctions, 3'-flap structures and aberrant replication fork structures. This protein may be involved in repairing DNA damage and in maintaining genomic stability. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:36928418-36934787
Strand Reverse strand
Band
Transcripts
ENSBTAT00000065898 ENSBTAP00000055580
ENSBTAT00000028957 ENSBTAP00000028957
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0004518 nuclease activity
GO:0005515 protein binding
Biological Process
GO:0072429 response to intra-S DNA damage checkpoint signaling
GO:0090305 nucleic acid phosphodiester bond hydrolysis
Cellular Component
GO:0000790 nuclear chromatin
GO:0005634 nucleus
GO:0005720 nuclear heterochromatin
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
Homologous recombination pathway
Homologous recombination pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.53032
RefSeq NM_001103332 XM_005220479
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas