Version 5.4
Bos taurus Gene: ERF
Summary
InnateDB Gene IDBG-638595.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ERF
Gene Name ETS domain-containing transcription factor ERF
Synonyms ETF1
Species Bos taurus
Ensembl Gene ENSBTAG00000000332
Encoded Proteins
IDBP-690668
Ets2 repressor factor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000105722:
Members of the ETS family of transcription factors, such as ERF, regulate cell proliferation and differentiation. They share a highly conserved DNA-binding domain, the ETS domain, that recognizes the sequence GGAA/T (de Castro et al., 1997 [PubMed 9192842]). For further information on ETS transcription factors, see ETS1 (MIM 164720).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:51350921-51357467
Strand Forward strand
Band
Transcripts
ENSBTAT00000000437 ENSBTAP00000000437
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003714 transcription corepressor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001701 in utero embryonic development
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006366 transcription from RNA polymerase II promoter
GO:0010668 ectodermal cell differentiation
GO:0030154 cell differentiation
GO:0060707 trophoblast giant cell differentiation
GO:0060710 chorio-allantoic fusion
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000105722
View Gene Order
ENSMUSG00000040857
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_120956
Cellular responses to stress pathway
REACT_169325
Oncogene Induced Senescence pathway
REACT_169274
Cellular Senescence pathway
REACT_188957
Cellular responses to stress pathway
REACT_188971
Oncogene Induced Senescence pathway
REACT_188820
Cellular Senescence pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1MET2
UniProt Splice Variant
Entrez Gene 789798
UniGene Bt.79023
RefSeq NM_001205465
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02047212 DAAA02047213
GenPept
RNA Seq Atlas 789798

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca