Version 5.4
Bos taurus Gene: CACNG3
Summary
InnateDB Gene IDBG-638639.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CACNG3
Gene Name Voltage-dependent calcium channel gamma-3 subunit
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000001404
Encoded Proteins
IDBP-690720
Voltage-dependent calcium channel gamma-3 subunit
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000006116:
The protein encoded by this gene is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family. This gene is a susceptibility locus for childhood absence epilepsy. [provided by RefSeq, Dec 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 25:22178045-22278773
Strand Forward strand
Band
Transcripts
ENSBTAT00000001841 ENSBTAP00000001841
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005244 voltage-gated ion channel activity
GO:0005262 calcium channel activity
Biological Process
GO:0006810 transport
GO:0006811 ion transport
GO:0006816 calcium ion transport
GO:0034765 regulation of ion transmembrane transport
GO:0070588 calcium ion transmembrane transport
GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0032281 alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000006116
View Gene Order
ENSMUSG00000066189
View Gene Order
Pathways
NETPATH
REACTOME
REACT_223058
Transmission across Chemical Synapses pathway
REACT_202705
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
REACT_225032
Neuronal System pathway
REACT_219681
Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity pathway
REACT_214196
Trafficking of AMPA receptors pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_18307
Trafficking of AMPA receptors pathway
REACT_13685
Neuronal System pathway
REACT_13477
Transmission across Chemical Synapses pathway
REACT_15370
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
REACT_18347
Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity pathway
KEGG
hsa04010
MAPK signaling pathway pathway
hsa05412
Arrhythmogenic right ventricular cardiomyopathy (ARVC) pathway
hsa05410
Hypertrophic cardiomyopathy (HCM) pathway
hsa04260
Cardiac muscle contraction pathway
hsa05414
Dilated cardiomyopathy pathway
mmu04010
MAPK signaling pathway pathway
mmu04260
Cardiac muscle contraction pathway
mmu05412
Arrhythmogenic right ventricular cardiomyopathy (ARVC) pathway
mmu05410
Hypertrophic cardiomyopathy (HCM) pathway
mmu05414
Dilated cardiomyopathy pathway
INOH
INOH website
GPCR Dopamine D1like receptor signaling pathway pathway
INOH website
GPCR Dopamine D1like receptor signaling pathway pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.64394
RefSeq NM_001078014
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca