Version 5.4
Bos taurus Gene: DSTN
Summary
InnateDB Gene IDBG-638717.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DSTN
Gene Name Destrin
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000015434
Encoded Proteins
IDBP-690807
Destrin
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000125868:
The product of this gene belongs to the actin-binding proteins ADF family. This family of proteins is responsible for enhancing the turnover rate of actin in vivo. This gene encodes the actin depolymerizing protein that severs actin filaments (F-actin) and binds to actin monomers (G-actin). Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:38259752-38284536
Strand Forward strand
Band
Transcripts
ENSBTAT00000020512 ENSBTAP00000020512
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 54 interaction(s) predicted by orthology.
Predicted by orthology
Total 54 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
Biological Process
GO:0000910 cytokinesis
GO:0006928 cellular component movement
GO:0030042 actin filament depolymerization
GO:0030836 positive regulation of actin filament depolymerization
Cellular Component
GO:0005622 intracellular
GO:0005737 cytoplasm
GO:0015629 actin cytoskeleton
GO:0030864 cortical actin cytoskeleton
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000125868
View Gene Order
ENSMUSG00000015932
View Gene Order
Cross-References
SwissProt Q5E9D5
TrEMBL
UniProt Splice Variant
Entrez Gene 513267
UniGene
RefSeq NM_001015586
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC103074 BT020985
GenPept AAI03075 AAX09002
RNA Seq Atlas 513267

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca