Version 5.4
| Bos taurus Gene: RBBP7 | |||||||||||||||||
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| Summary | |||||||||||||||||
| InnateDB Gene | IDBG-638800.3 | ||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||
| Gene Symbol | RBBP7 | ||||||||||||||||
| Gene Name | Histone-binding protein RBBP7 | ||||||||||||||||
| Synonyms | |||||||||||||||||
| Species | Bos taurus | ||||||||||||||||
| Ensembl Gene | ENSBTAG00000002820 | ||||||||||||||||
| Encoded Proteins |
Histone-binding protein RBBP7
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| Protein Structure | |||||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||
| Entrez Gene | |||||||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000102054:
This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010] |
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| Gene Information | |||||||||||||||||
| Type | Protein coding | ||||||||||||||||
| Genomic Location | Chromosome X:133866652-133939151 | ||||||||||||||||
| Strand | Forward strand | ||||||||||||||||
| Band | |||||||||||||||||
| Transcripts |
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| Interactions | |||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 96 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathways | |||||||||||||||||
| NETPATH | |||||||||||||||||
| REACTOME |
Epigenetic regulation of gene expression pathway
Nucleosome assembly pathway
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
Deposition of new CENPA-containing nucleosomes at the centromere pathway
RNA Polymerase I Transcription pathway
Cellular responses to stress pathway
Gene Expression pathway
Chromatin organization pathway
HDACs deacetylate histones pathway
Cell Cycle pathway
Cellular Senescence pathway
Oxidative Stress Induced Senescence pathway
HATs acetylate histones pathway
RNA Polymerase I Transcription Initiation pathway
Chromosome Maintenance pathway
PRC2 methylates histones and DNA pathway
RMTs methylate histone arginines pathway
RNA Polymerase I Promoter Clearance pathway
Chromatin modifying enzymes pathway
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| KEGG | |||||||||||||||||
| INOH | |||||||||||||||||
| PID NCI | |||||||||||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||||||||||
| NETPATH |
EGFR1 pathway
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| REACTOME |
Deposition of new CENPA-containing nucleosomes at the centromere pathway
RNA Polymerase I Transcription Initiation pathway
HATs acetylate histones pathway
Cellular responses to stress pathway
PRC2 methylates histones and DNA pathway
RNA Polymerase I Transcription pathway
Chromosome Maintenance pathway
Nucleosome assembly pathway
Epigenetic regulation of gene expression pathway
RNA Polymerase I Promoter Clearance pathway
Cell Cycle pathway
HDACs deacetylate histones pathway
Cellular Senescence pathway
Chromatin organization pathway
RMTs methylate histone arginines pathway
Chromatin modifying enzymes pathway
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
Oxidative Stress Induced Senescence pathway
Gene Expression pathway
RNA Polymerase I Transcription pathway
Oxidative Stress Induced Senescence pathway
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
Mus musculus biological processes pathway
NoRC negatively regulates rRNA expression pathway
Chromatin organization pathway
Chromosome Maintenance pathway
Cellular responses to stress pathway
HATs acetylate histones pathway
PRC2 methylates histones and DNA pathway
Cell Cycle pathway
NoRC negatively regulates rRNA expression pathway
Chromatin modifying enzymes pathway
Cellular Senescence pathway
Epigenetic regulation of gene expression pathway
Gene Expression pathway
Negative epigenetic regulation of rRNA expression pathway
Nucleosome assembly pathway
Deposition of new CENPA-containing nucleosomes at the centromere pathway
RMTs methylate histone arginines pathway
HDACs deacetylate histones pathway
RNA Polymerase I Promoter Clearance pathway
RNA Polymerase I Transcription Initiation pathway
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| KEGG | |||||||||||||||||
| INOH | |||||||||||||||||
| PID NCI |
Signaling events mediated by HDAC Class I
Regulation of nuclear SMAD2/3 signaling
Hedgehog signaling events mediated by Gli proteins
Regulation of Telomerase
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| Cross-References | |||||||||||||||||
| SwissProt | |||||||||||||||||
| TrEMBL | |||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||
| Entrez Gene | |||||||||||||||||
| UniGene | Bt.4908 | ||||||||||||||||
| RefSeq | NM_001034638 | ||||||||||||||||
| HUGO | |||||||||||||||||
| OMIM | |||||||||||||||||
| CCDS | |||||||||||||||||
| HPRD | |||||||||||||||||
| IMGT | |||||||||||||||||
| EMBL | |||||||||||||||||
| GenPept | |||||||||||||||||
| RNA Seq Atlas | |||||||||||||||||