Version 5.4
Bos taurus Gene: SLC24A3
Summary
InnateDB Gene IDBG-638865.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC24A3
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000011882
Encoded Proteins
IDBP-690980
solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000185052:
Plasma membrane sodium/calcium exchangers are an important component of intracellular calcium homeostasis and electrical conduction. Potassium-dependent sodium/calcium exchangers such as SLC24A3 are believed to transport 1 intracellular calcium and 1 potassium ion in exchange for 4 extracellular sodium ions (Kraev et al., 2001 [PubMed 11294880]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:39202450-39632869
Strand Forward strand
Band
Transcripts
ENSBTAT00000015768 ENSBTAP00000015768
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0008273 calcium, potassium:sodium antiporter activity
Biological Process
GO:0035725 sodium ion transmembrane transport
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000185052
View Gene Order
ENSMUSG00000063873
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_19320
Sodium/Calcium exchangers pathway
REACT_19397
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_19118
SLC-mediated transmembrane transport pathway
REACT_247550
SLC-mediated transmembrane transport pathway
REACT_251788
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
REACT_253400
Transmembrane transport of small molecules pathway
REACT_236234
Sodium/Calcium exchangers pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E1BGG7
UniProt Splice Variant
Entrez Gene 616407
UniGene Bt.43764
RefSeq XM_002692137 XM_005194317 XM_005194318 XM_005214377 XM_005214378 XM_868421
HUGO HGNC:10977
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02035737 DAAA02035738 DAAA02035739 DAAA02035740 DAAA02035741 DAAA02035742 DAAA02035743 DAAA02035744
GenPept
RNA Seq Atlas 616407

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca