Version 5.4
| Bos taurus Gene: BT.53493 | |||||||
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| Summary | |||||||
| InnateDB Gene | IDBG-638928.3 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | BT.53493 | ||||||
| Gene Name | gelsolin isoform a precursor | ||||||
| Synonyms | |||||||
| Species | Bos taurus | ||||||
| Ensembl Gene | ENSBTAG00000019915 | ||||||
| Encoded Proteins |
gelsolin a
gelsolin a
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| Protein Structure | |||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||
| Entrez Gene | |||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000148180:
The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||
| Type | Protein coding | ||||||
| Genomic Location | Chromosome 8:112578066-112639758 | ||||||
| Strand | Forward strand | ||||||
| Band | |||||||
| Transcripts |
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| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 33 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||
| NETPATH |
AndrogenReceptor pathway
EGFR1 pathway
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| REACTOME |
Caspase-mediated cleavage of cytoskeletal proteins pathway
Apoptotic cleavage of cellular proteins pathway
Apoptotic execution phase pathway
Amyloids pathway
Apoptosis pathway
Disease pathway
Apoptosis pathway
Disease pathway
Amyloids pathway
Apoptotic cleavage of cellular proteins pathway
Caspase-mediated cleavage of cytoskeletal proteins pathway
Apoptotic execution phase pathway
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| KEGG |
Regulation of actin cytoskeleton pathway
Fc gamma R-mediated phagocytosis pathway
Regulation of actin cytoskeleton pathway
Fc gamma R-mediated phagocytosis pathway
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| INOH | |||||||
| PID NCI |
Caspase Cascade in Apoptosis
Coregulation of Androgen receptor activity
N-cadherin signaling events
Osteopontin-mediated events
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| Cross-References | |||||||
| SwissProt | |||||||
| TrEMBL | |||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | |||||||
| UniGene | Bt.103692 Bt.53493 | ||||||
| RefSeq | NM_001034627 NM_001113284 XM_005210607 XM_005210608 | ||||||
| HUGO | |||||||
| OMIM | |||||||
| CCDS | |||||||
| HPRD | |||||||
| IMGT | |||||||
| EMBL | |||||||
| GenPept | |||||||
| RNA Seq Atlas | |||||||