InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: GDI2

Summary

InnateDB Gene

IDBG-639226.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GDI2

Gene Name

Rab GDP dissociation inhibitor beta

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000005316

Encoded Proteins

IDBP-691361

Rab GDP dissociation inhibitor beta

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000057608:
GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI2 is ubiquitously expressed. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 13:43302440-43331090

Strand

Forward strand

Band

Transcripts

ENSBTAT00000006992

ENSBTAP00000006992

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 31 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	31 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005093	Rab GDP-dissociation inhibitor activity
GO:0005096	GTPase activator activity
GO:0005097	Rab GTPase activator activity
GO:0005515	protein binding
GO:0044822	poly(A) RNA binding