Bos taurus Gene: SLC27A4
Summary
InnateDB Gene IDBG-639381.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC27A4
Gene Name long-chain fatty acid transport protein 4
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000015436
Encoded Proteins
solute carrier family 27 (fatty acid transporter), member 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000167114:
This gene encodes a member of a family of fatty acid transport proteins, which are involved in translocation of long-chain fatty acids cross the plasma membrane. This protein is expressed at high levels on the apical side of mature enterocytes in the small intestine, and appears to be the principal fatty acid transporter in enterocytes. Clinical studies suggest this gene as a candidate gene for the insulin resistance syndrome. Mutations in this gene have been associated with ichthyosis prematurity syndrome. [provided by RefSeq, Apr 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:98957840-98971732
Strand Forward strand
Band
Transcripts
ENSBTAT00000020526 ENSBTAP00000020526
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004467 long-chain fatty acid-CoA ligase activity
GO:0031957 very long-chain fatty acid-CoA ligase activity
Biological Process
GO:0000038 very long-chain fatty acid metabolic process
GO:0001579 medium-chain fatty acid transport
GO:0001676 long-chain fatty acid metabolic process
GO:0006631 fatty acid metabolic process
GO:0008152 metabolic process
GO:0015909 long-chain fatty acid transport
GO:0042760 very long-chain fatty acid catabolic process
GO:0043588 skin development
GO:0044539 long-chain fatty acid import
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005902 microvillus
GO:0016020 membrane
GO:0031526 brush border membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Transport of fatty acids pathway
Transport of vitamins, nucleosides, and related molecules pathway
Transmembrane transport of small molecules pathway
SLC-mediated transmembrane transport pathway
SLC-mediated transmembrane transport pathway
Transport of vitamins, nucleosides, and related molecules pathway
Transmembrane transport of small molecules pathway
Transport of fatty acids pathway
KEGG
PPAR signaling pathway pathway
Fat digestion and absorption pathway
PPAR signaling pathway pathway
Fat digestion and absorption pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.104871
RefSeq NM_001075667 XM_003582834
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas