Bos taurus Gene: FOSB
Summary
InnateDB Gene IDBG-639475.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FOSB
Gene Name protein fosB
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000008182
Encoded Proteins
protein fosB
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000125740:
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:53501995-53508395
Strand Forward strand
Band
Transcripts
ENSBTAT00000010762 ENSBTAP00000010762
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0071277 cellular response to calcium ion
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
TGF_beta_Receptor pathway
BCR pathway
REACTOME
KEGG
Osteoclast differentiation pathway
Osteoclast differentiation pathway
INOH
CD4 T cell receptor signaling pathway
CD4 T cell receptor signaling pathway
PID NCI
AP-1 transcription factor network
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.52251
RefSeq NM_001102248
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas