Version 5.4
Bos taurus Gene: CLEC1B
Summary
InnateDB Gene IDBG-639588.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CLEC1B
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000030423
Encoded Proteins
IDBP-691768
C-type lectin domain family 1, member B
IDBP-691773
C-type lectin domain family 1, member B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
Summary
PMID 21728173
[Homo sapiens] CLEC1B is expressed in myeloid cells and acts as a SYK-coupled C-type lectin receptor (CLR) able to modulate Toll-like receptor (TLR) signaling and inflammatory responses. ( Demonstrated in murine model)
PMID 21728173
[Mus musculus] Clec1b is expressed in myeloid cells and acts as a Syk-coupled C-type lectin receptor (CLR) able to modulate Toll-like receptor (TLR) signaling and inflammatory responses.
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000165682:
Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1; MIM 602894) and NKG2D (KLRC4; MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in myeloid cells and NK cells (Colonna et al., 2000 [PubMed 10671229]).[supplied by OMIM, Jan 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:100346463-100355669
Strand Reverse strand
Band
Transcripts
ENSBTAT00000030538 ENSBTAP00000030517
ENSBTAT00000053034 ENSBTAP00000050331
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0030246 carbohydrate binding
Biological Process
GO:0030220 platelet formation
Cellular Component
GO:0005887 integral component of plasma membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000165682
View Gene Order
ENSMUSG00000030159
View Gene Order
Cross-References
SwissProt
TrEMBL E1BGA8
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq
HUGO HGNC:24356
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02014361
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca