Version 5.4
Bos taurus Gene: BT.89187
Summary
InnateDB Gene IDBG-639629.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.89187
Gene Name kynurenine--oxoglutarate transaminase 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000036101
Encoded Proteins
IDBP-691812
kynurenine--oxoglutarate transaminase 1
IDBP-691816
kynurenine--oxoglutarate transaminase 1
IDBP-691819
kynurenine--oxoglutarate transaminase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000171097:
This gene encodes a cytosolic enzyme that is responsible for the metabolism of cysteine conjugates of certain halogenated alkenes and alkanes. This metabolism can form reactive metabolites leading to nephrotoxicity and neurotoxicity. Increased levels of this enzyme have been linked to schizophrenia. Multiple transcript variants that encode different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:99340500-99411162
Strand Reverse strand
Band
Transcripts
ENSBTAT00000050592 ENSBTAP00000047274
ENSBTAT00000025004 ENSBTAP00000025004
ENSBTAT00000050582 ENSBTAP00000047262
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0009058 biosynthetic process
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000171097
View Gene Order
ENSMUSG00000039648
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_916
Tryptophan catabolism pathway
REACT_238
Amino acid synthesis and interconversion (transamination) pathway
REACT_1786
Phenylalanine and tyrosine catabolism pathway
REACT_121117
Abnormal metabolism in phenylketonuria pathway
REACT_13
Metabolism of amino acids and derivatives pathway
REACT_111217
Metabolism pathway
REACT_116125
Disease pathway
REACT_189085
Disease pathway
REACT_261966
Phenylalanine and tyrosine catabolism pathway
REACT_188937
Metabolism pathway
REACT_232845
Metabolism of amino acids and derivatives pathway
REACT_240936
Tryptophan catabolism pathway
REACT_189094
Abnormal metabolism in phenylketonuria pathway
REACT_239550
Amino acid synthesis and interconversion (transamination) pathway
KEGG
hsa00380
Tryptophan metabolism pathway
hsa00450
Selenocompound metabolism pathway
mmu00380
Tryptophan metabolism pathway
mmu00450
Selenocompound metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.89187 Bt.89188 Bt.99565
RefSeq NM_001077978 XM_001790512 XM_003585361 XM_005194024 XM_005194027
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca