Version 5.4
Bos taurus Gene: VAX1
Summary
InnateDB Gene IDBG-640236.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol VAX1
Gene Name ventral anterior homeobox 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000013875
Encoded Proteins
IDBP-692469
ventral anterior homeobox 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000148704:
This gene encodes a homeo-domain containing protein from a class of homeobox transcription factors which are conserved in vertebrates. Genes of this family are involved in the regulation of body development and morphogenesis. The most conserved genes, called HOX genes are found in special gene clusters. This gene belongs to the VAX subfamily and lies in the vicinity of the EMX homeobox gene family. Another member of VAX family is located on chromosome 2. The encoded protein may play an important role in the development of anterior ventral forebrain and visual system. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 26:37796165-37801021
Strand Reverse strand
Band
Transcripts
ENSBTAT00000032764 ENSBTAP00000032693
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0031490 chromatin DNA binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001764 neuron migration
GO:0006355 regulation of transcription, DNA-templated
GO:0007399 nervous system development
GO:0007406 negative regulation of neuroblast proliferation
GO:0007411 axon guidance
GO:0007417 central nervous system development
GO:0007420 brain development
GO:0030154 cell differentiation
GO:0035914 skeletal muscle cell differentiation
GO:0043010 camera-type eye development
GO:0060021 palate development
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000148704
View Gene Order
ENSMUSG00000006270
View Gene Order
Cross-References
SwissProt
TrEMBL E1B853
UniProt Splice Variant
Entrez Gene 782056
UniGene Bt.106422
RefSeq NM_001191142
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02059342 DAAA02059343
GenPept
RNA Seq Atlas 782056

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca