InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: SLC18A2

Summary

InnateDB Gene

IDBG-640240.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SLC18A2

Gene Name

synaptic vesicular amine transporter

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000004739

Encoded Proteins

IDBP-692483

synaptic vesicular amine transporter

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000165646:
The vesicular monoamine transporter acts to accumulate cytosolic monoamines into synaptic vesicles, using the proton gradient maintained across the synaptic vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (summary by Peter et al., 1993 [PubMed 7905859]). See also SLC18A1 (MIM 193002).[supplied by OMIM, Jan 2011]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 26:37895810-37936012

Strand

Forward strand

Band

Transcripts

ENSBTAT00000006221

ENSBTAP00000006221

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0015238	drug transmembrane transporter activity

Biological Process

GO:0001975	response to amphetamine
GO:0006855	drug transmembrane transport
GO:0007626	locomotory behavior
GO:0009636	response to toxic substance
GO:0009791	post-embryonic development
GO:0015893	drug transport
GO:0016265	death
GO:0055085	transmembrane transport