InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: SNRPB

Summary

InnateDB Gene

IDBG-640309.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SNRPB

Gene Name

Small nuclear ribonucleoprotein-associated protein

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000001038

Encoded Proteins

IDBP-692557

small nuclear ribonucleoprotein polypeptides B and B1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000125835:
The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene. [provided by RefSeq, Jul 2008]
The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B\') have been found for this gene. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 13:53134613-53143629

Strand

Forward strand

Band

Transcripts

ENSBTAT00000001379

ENSBTAP00000001379

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 62 interaction(s) predicted by orthology.

Predicted by orthology
Total	62 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0005515	protein binding
GO:0044822	poly(A) RNA binding
GO:0071208	histone pre-mRNA DCP binding

Biological Process

GO:0000387

spliceosomal snRNP assembly

Cellular Component

GO:0005634	nucleus
GO:0005683	U7 snRNP
GO:0005685	U1 snRNP
GO:0005687	U4 snRNP
GO:0005689	U12-type spliceosomal complex
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0030529	ribonucleoprotein complex
GO:0034709	methylosome
GO:0034719	SMN-Sm protein complex
GO:0070062	extracellular vesicular exosome
GO:0071013	catalytic step 2 spliceosome
GO:0071204	histone pre-mRNA 3'end processing complex