Version 5.4
| Bos taurus Gene: BRWD2 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-640422.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | BRWD2 | ||||||||
| Gene Name | WD repeat-containing protein 11 | ||||||||
| Synonyms | BRWD2; PHIP | ||||||||
| Species | Bos taurus | ||||||||
| Ensembl Gene | ENSBTAG00000021540 | ||||||||
| Encoded Proteins |
WD repeat-containing protein 11
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000120008:
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is located in the chromosome 10q25-26 region, which is frequently deleted in gliomas and tumors of other tissues, and is disrupted by the t(10;19) translocation rearrangement in glioblastoma cells. The gene location suggests that it is a candidate gene for the tumor suppressor locus. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 26:41212406-41271588 | ||||||||
| Strand | Forward strand | ||||||||
| Band | |||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | A6QLS8 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 525169 | ||||||||
| UniGene | Bt.19088 | ||||||||
| RefSeq | NM_001101122 XM_005225811 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | BC148072 DAAA02059434 | ||||||||
| GenPept | AAI48073 | ||||||||
| RNA Seq Atlas | 525169 | ||||||||