InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: VAMP1

Summary

InnateDB Gene

IDBG-640489.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

VAMP1

Gene Name

Vesicle-associated membrane protein 1

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000014603

Encoded Proteins

IDBP-692755

Vesicle-associated membrane protein 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000139190:
Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. VAMP1 is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Multiple alternative splice variants that encode proteins with alternative carboxy ends have been described, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008]
Synapotobrevins, syntaxins, and the synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Mutations in this gene are associated with autosomal dominant spastic ataxia 1. Multiple alternative splice variants have been described, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2014]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 5:104285969-104292908

Strand

Forward strand

Band

Transcripts

ENSBTAT00000019599

ENSBTAP00000019599

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0016192	vesicle-mediated transport
GO:0035493	SNARE complex assembly

Cellular Component

GO:0005739	mitochondrion
GO:0009986	cell surface
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030054	cell junction
GO:0030659	cytoplasmic vesicle membrane
GO:0030672	synaptic vesicle membrane
GO:0031410	cytoplasmic vesicle
GO:0043005	neuron projection
GO:0045202	synapse