Version 5.4
Bos taurus Gene: DSCR3
Summary
InnateDB Gene IDBG-640549.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DSCR3
Gene Name Down syndrome critical region protein 3
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000004791
Encoded Proteins
IDBP-692824
Down syndrome critical region protein 3
IDBP-692826
Down syndrome critical region protein 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000157538:
The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and mental retardation. The DSCR3 (Down syndrome critical region gene 3) gene is found in this region and is predictated to contain eight exons. DSCR3 is expressed in most tissues examined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:151164860-151199134
Strand Reverse strand
Band
Transcripts
ENSBTAT00000050520 ENSBTAP00000047205
ENSBTAT00000006292 ENSBTAP00000006292
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000157538
View Gene Order
ENSMUSG00000022898
View Gene Order
Cross-References
SwissProt
TrEMBL Q58DN0
UniProt Splice Variant
Entrez Gene 507647
UniGene Bt.6631
RefSeq NM_001040510
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BT021567 DAAA02003581 DAAA02003582 DAAA02003583
GenPept AAX46414
RNA Seq Atlas 507647

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca