Version 5.4
| Bos taurus Gene: SGMS2 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-640574.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | SGMS2 | ||||||||
| Gene Name | phosphatidylcholine:ceramide cholinephosphotransferase 2 | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Gene | ENSBTAG00000016805 | ||||||||
| Encoded Proteins |
sphingomyelin synthase 2
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000164023:
Sphingomyelin, a major component of cell and Golgi membranes, is made by the transfer of phosphocholine from phosphatidylcholine onto ceramide, with diacylglycerol as a side product. The protein encoded by this gene is an enzyme that catalyzes this reaction primarily at the cell membrane. The synthesis is reversible, and this enzyme can catalyze the reaction in either direction. The encoded protein is required for cell growth. Three transcript variants encoding the same protein have been found for this gene. There is evidence for more variants, but the full-length nature of their transcripts has not been determined.[provided by RefSeq, Oct 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 6:18547613-18568780 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | |||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
Sphingolipid de novo biosynthesis pathway
Sphingolipid metabolism pathway
Metabolism of lipids and lipoproteins pathway
Metabolism pathway
Sphingolipid de novo biosynthesis pathway
Metabolism pathway
Sphingolipid metabolism pathway
Metabolism of lipids and lipoproteins pathway
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| KEGG |
Sphingolipid metabolism pathway
Sphingolipid metabolism pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | E1BNX6 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 520954 | ||||||||
| UniGene | Bt.43070 Bt.68060 | ||||||||
| RefSeq | NM_001205877 XM_005207610 XM_005207611 XM_005207612 XM_005207613 XM_005207614 XM_005207615 XM_005207616 XM_005207617 XM_005207618 XM_005207619 XM_005207620 XM_005207621 XM_005207622 XM_005207623 | ||||||||
| HUGO | HGNC:28395 | ||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | DAAA02016617 | ||||||||
| GenPept | |||||||||
| RNA Seq Atlas | 520954 | ||||||||