Bos taurus Gene: AGFG2
Summary
InnateDB Gene IDBG-640585.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AGFG2
Gene Name arf-GAP domain and FG repeats-containing protein 2
Synonyms HRBL
Species Bos taurus
Ensembl Gene ENSBTAG00000000713
Encoded Proteins
ArfGAP with FG repeats 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000106351:
This gene is a member of the HIV-1 Rev binding protein (HRB) family and encodes a protein with one Arf-GAP zinc finger domain, several phe-gly (FG) motifs, and four asn-pro-phe (NPF) motifs. This protein interacts with Eps15 homology (EH) domains and plays a role in the Rev export pathway, which mediates the nucleocytoplasmic transfer of proteins and RNAs. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Feb 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 25:36528495-36547791
Strand Reverse strand
Band
Transcripts
ENSBTAT00000000957 ENSBTAP00000000957
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008060 ARF GTPase activator activity
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0032312 regulation of ARF GTPase activity
GO:0043547 positive regulation of GTPase activity
Cellular Component
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Cross-References
SwissProt
TrEMBL F1MS35
UniProt Splice Variant
Entrez Gene 510361
UniGene
RefSeq XM_005225064 XM_005225065
HUGO HGNC:5177
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02058279
GenPept
RNA Seq Atlas 510361