Bos taurus Gene: BCL2L12
Summary
InnateDB Gene IDBG-640641.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BCL2L12
Gene Name bcl-2-like protein 12
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000006638
Encoded Proteins
bcl-2-like protein 12
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000126453:
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a Bcl-2 homology domain 2 (BH2). The function of this gene has not yet been determined. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:56523439-56530499
Strand Forward strand
Band
Transcripts
ENSBTAT00000008723 ENSBTAP00000008723
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0002039 p53 binding
GO:0005515 protein binding
Biological Process
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process
GO:2000773 negative regulation of cellular senescence
Cellular Component
GO:0005634 nucleus
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Cross-References
SwissProt
TrEMBL A6QPJ9
UniProt Splice Variant
Entrez Gene 533338
UniGene Bt.62321
RefSeq NM_001101148 XM_005219307 XM_005219308 XM_005219309
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC149358 DAAA02047482
GenPept AAI49359
RNA Seq Atlas 533338