InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: SLC25A12

Summary

InnateDB Gene

IDBG-640691.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SLC25A12

Gene Name

calcium-binding mitochondrial carrier protein Aralar1

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000016762

Encoded Proteins

IDBP-692985

calcium-binding mitochondrial carrier protein Aralar1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000115840:
This gene encodes a calcium-binding mitochondrial carrier protein. The encoded protein localizes to the mitochondria and is involved in the exchange of aspartate for glutamate across the inner mitochondrial membrane. Polymorphisms in this gene may be associated with autism, and mutations in this gene may also be a cause of global cerebral hypomyelination. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Apr 2012]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 2:24678582-24777204

Strand

Forward strand

Band

Transcripts

ENSBTAT00000022292

ENSBTAP00000022292

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.

Predicted by orthology
Total	11 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005313	L-glutamate transmembrane transporter activity
GO:0005509	calcium ion binding
GO:0015183	L-aspartate transmembrane transporter activity

Biological Process

GO:0006810	transport
GO:0015810	aspartate transport
GO:0015813	L-glutamate transport
GO:0043490	malate-aspartate shuttle
GO:0051592	response to calcium ion
GO:0055085	transmembrane transport